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Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Antibody Class: IgG2aκ ARP-11422 is a monoclonal antibody to dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN). The B cell hybridoma was generated by the fusion of SP2/0 mouse myeloma cells with immunized BALB/c mouse splenocytes. The mice were inoculated with recombinant vaccinia virus expressing full-length DC-SIGN.
ARP-11422 does not cross react with L-SIGN.
Note: ARP-11422 may be stored at 4°C for short-term storage and at -80°C for long term storage. Avoid freeze-thaw cycles as reagent degradation may result.
Note: The user should determine the optimal concentration of ARP-11422 for any application.
Each vial of ARP-11422 contains approximately 66 µg of purified antibody at 0.66 mg per mL in PBS. Please refer to the appropriate data sheet for lot-specific information.
Granelli-Piperno, A., et al. “Dendritic Cell-specific Intercellular Adhesion Molecule 3-Grabbing Nonintegrin/CD209 is Abundant on Macrophages in the Normal Human Lymph Node and is Not Required for Dendritic Cell Stimulation of the Mixed Leukocyte Reaction.”J. Immunol. 175 (2005): 4265-4273. PubMed: 16177066.
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